Our mission is to integrate the innovative PermeaPad® technology (biomimetic barriers) into as many applications as possible. We want to show our customers how simple and useful in vitro permeation assays are. Our goal is to accelerate drug development and support our customers in the implementation of the 3R’s (Refining, Replacing and Reducing) of animal testing through the technology.
Microscopic image of a wetted PermeaPad® GIT Barrier.
My research focus is centered around solid dosage forms, with a specific emphasis on the development of novel biomimetic models and analytical methods relevant to the study of drug release and absorption kinetics. Our foremost objective is to improve the optimization of drug formulations while concurrently reducing animal-based testing practices via the enhancement of our ability to foresee drug bioavailability following oral administration.
To achieve this goal, we employ PlainPlates and PermaPad® in multiple formats to authentically simulate the gastrointestinal environment within which orally delivered drugs operate. Through our innovative approach, we explore the kinetic mechanisms of drug molecule release, drug colloid, and particle co-permeation. The resultant data provides unequivocal insight into the absorption of various formulations, enabling researchers to make informed decisions regarding their efficacy and safety.
My interests include physical pharmacy, as well as solubilization techniques that aim to increase the solubility of poorly soluble compounds. Furthermore, I have also studied the development of new in vitro tools, such as the PermeaPad® tool, for investigating drug permeability.
Recently, I have pioneered a unique approach for parameterizing drug diffusivity in unmixed media. This innovation has the potential to revolutionize the drug delivery industry.
If you wish to collaborate with me, please do not hesitate to contact me at: email@example.com
The barrier is stored at room temperature. It is ready for use immediately: No barrier preparation necessary.
Using permeation data reduces animal testing.
It is possible to simulate in vivo situations. The barrier can withstand harsh environmental conditions.
These products are ideal for drug permeability experiments.