Menu
Our biomimetic barrier enables an innovative approach for in vitro permeability assays*. The barrier simulates the cell barrier of the gastrointestinal tract, oral, and nasal mucosa. It was developed to offer science/research a way to obtain consistent and reproducible results. The PermeaPad® Barrier is ready-to-use, so no pre-treatment time needs to be scheduled. It is very robust and stable against solvents and biorelevant solutions and can be stored at room temperature. Due to the barrier’s robustness, fluids/environmental parameters can be chosen to simulate in vivo situations without the need for animal experiments. The barrier can be applied in a conventional vertical diffusion cell (e.g. Franz cell), side-by-side diffusion cell, or other setups.
*For research purposes only. Not for use in diagnostic procedures.
The 96-well microtiter plate enables a breakthrough in high-throughput permeability screening. The innovative design and biomimetic barriers integrated into the plate (PermeaPad® GIT Barrier) enable in vitro permeability assays*. The PermeaPad® GIT Barrier simulates passive substance transport. Measurements with the PermeaPad® GIT Plate are easy, fast, and reproducible. Due to the robustness of the barrier, fluids/environmental parameters can be chosen to simulate in vivo situations without the need for animal testing. The PermeaPad® GIT Plate can be used for screening and ranking of new drug compounds (NCEs) and formulations. Additionally, it can be used with pipetting platforms.
*For research purposes only. Not for use in diagnostic procedures.
The PermeaPlain Barrier enables the efficient investigation of the passive mass transfer of drugs based on a permeable regenerated cellulose hydrate. Regardless of the polarity of the substance, the diffusion of each drug can be analyzed through a membrane*. Therefore, it is particularly suitable for the in vitro release test (IVRT). The measurements with the barrier are easy, fast, and reproducible. The simulation of passive mass transport can be carried out by applying the PermeaPlain Barrier in a conventional vertical diffusion cell (e.g., Franz cell), side-by-side diffusion cell, or other setups.
*For research purposes only. Not for use in diagnostic procedures.
Copyright © PHABIOC GmbH, 2023